Immunofluorescent localization of gastrin in rabbit antropyloric mucosa to argyrophil cells exhibiting formaldehyde-ozone-induced fluorescence |
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| Authors: | L I Larsson F Sundler R Håkanson J F Rehfeld F Stadil |
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| Institution: | (1) Departments of Histology and Pharmacology, University of Lund, Lund, Sweden;(2) Department of Clinical Chemistry, Bispebjerg Hospital, Copenhagen, Denmark;(3) Department of Gastroenterology (C), Rigshospital, Copenhagen, Denmark |
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| Abstract: | Summary The cellular localization of gastrin in the rabbit pyloric antrum was established by immunofluorescence. The gastrin cell was argyrophil (Grimelius technique) and identical with a previously described cell type that emits fluorescence upon combined formaldehydeozone treatment, a feature that has been interpreted as indicating storage of peptides with NH2-terminal tryptophan. The identity of the peptides and its relation to gastrin is unknown. |
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