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Mechanism of Host Cell MAPK/ERK-2 Incorporation into Lentivirus Particles: Characterization of the Interaction between MAPK/ERK-2 and Proline-Rich-Domain Containing Capsid Region of Structural Protein Gag
Authors:Pankaj Gupta  Palakurthy Rajendrakumar  Ashish V Tendulkar  Reinhold E Schmidt  S Mahalingam
Institution:
  • 1 Laboratory of Molecular Virology and Cell Biology, Department of Biotechnology, Indian Institute of Technology-Madras, Chennai 600 036, India
  • 2 Department of Computer Sciences and Engineering, Indian Institute of Technology-Madras, Chennai 600 036, India
  • 3 Advanced Bioscience Laboratories Inc., Kensington, MD 20895, USA
  • 4 Department of Immunology and Rheumatology, Hannover Medical School, Hannover, Germany
  • 5 NanoBio Diagnostics, West Chester, PA 19382, USA
  • Abstract:
    Keywords:HIV  human immunodeficiency virus  SIV  simian immunodeficiency virus  MAPK  mitogen-activated protein kinase  ERK-2  extracellular signal-regulated kinase 2  VLP  virus-like particle  CA  capsid  PIC  preintegration complex  MA  matrix  HTLV  human T-lymphotropic virus  DMEM  Dulbecco's modified Eagle's medium  GFP  green fluorescent protein  NC  nucleocapsid  GST  glutathione S-transferase  Cyp-A  cyclophilin-A  DAPI  4&prime    6-diamidino-2-phenylindole  PDB  Protein Data Bank
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