DNA homology between Candida albicans strains: Evidence to justify the synonymous status of C. stellatoidea |
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| Authors: | Akiko Kamiyama Masakazu Niimi Michiko Tokunaga Hiroaki Nakayama |
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| Institution: | (1) Department of Microbiology, School of Dentistry, Kagoshima University, 890 Kagoshima, Japan;(2) Department of Microbiology, School of Dentistry, Kyushu University, 812 Fukuoka, Japan |
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| Abstract: | Genetic relatedness between strains of C. albicans and C. stellatoidea was studied by measuring G + C content and overall sequence homology. G + C contents determined by high-performance liquid chromatography were 32.6 to 34.2% for 26 strains of C. albicans and 33.0 to 33.9% for eight strains of C. stellatoidea. DNA-DNA hybridization with two C. albicans and two C. stellatoidea probes revealed that all 34 test strains formed a single cluster in which the extents of hybridization with the heterologous probes ranged between 77.9 and 105.6% of those with the homologous probes. These results give support to the unification of C. albicans and C. stellatoidea into a single species. |
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| Keywords: | C albicans C stellatoidea DNA homology |
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