Combined phylogenetic and neighbourhood analysis of the hexose transporters and glucose sensors in yeasts |
| |
| Authors: | Margarida Palma,Marie-Line Seret,& Philippe V. Baret |
| |
| Affiliation: | Life Sciences Department, Centro de Recursos Microbiológicos, New University of Lisbon, Caparica, Portugal;and;Unitéde génétique (GENA-POPS), Facultéd'ingénierie biologique, agronomique et environnementale, Universitécatholique de Louvain, Louvain-la-Neuve, Belgium |
| |
| Abstract: | The sugar porter family in yeasts encompasses a wide variety of transporters including the hexose transporters and glucose sensors. We analysed a total of 75 members from both groups in nine hemiascomycetous species, with complete and well-annotated genomes: Saccharomyces cerevisiae, Candida glabrata, Zygosaccharomyces rouxii, Kluyveromyces thermotolerans, Saccharomyces kluyverii, Kluyveromyces lactis, Eremothecium gossypii, Debaryomyces hansenii and Yarrowia lipolytica . We present a model for the evolution of the hexose transporters and glucose sensors, supported by two types of complementary evidences: phylogeny and neighbourhood analysis. Five lineages of evolution were identified and discussed according to different mechanisms of gene evolution: lineage A for HXT1, HXT3 , HXT4, HXT5 , HXT6 and HXT7 ; lineage B for HXT2 and HXT10 ; lineage C for HXT8 ; lineage D for HXT14 ; and lineage E for SNF3 and RGT2 . |
| |
| Keywords: | sugar transporters glucose sensors neighbourhood analysis phylogeny HXT evolutionary lineages |
|
|
