Development of diagnostic methods based on a core antigen of hepatitis B, obtained by methods of genetic engineering |
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Authors: | V V Tsibinogin V Ia Loseva G P Borisova Ia V Kalis |
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Abstract: | The possibility of using recombinant HBcAg, synthesized in Escherichia coli, for diagnostic purposes has been studied. The antigen can be used in highly sensitive immunological assays for the detection of IgG and IgM antibodies to HBcAg. |
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