Expression pattern of XIRG, a marker for non-neural ectoderm |
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| Authors: | G Schmidt Klaus Richter |
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| Institution: | (1) Institute of Genetics and General Biology, University of Salzburg, Hellbrunnerstrasse 34, 5020 Salzburg, Austria e-mail: georg.schmidt@sbg.ac.at Tel.: +43-662-80445791, Fax: +43-662-8044144, AT |
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| Abstract: | XIRG (for Xenopus IRG) was cloned by screening a cDNA library of UV-ventralized stage 13 Xenopus laevis embryos for specifically ventrally expressed mRNAs. Embryonic XIRG mRNA expression is restricted to non-neural ectoderm at the gastrula and neurula stages. In adult X. laevis, XIRG mRNA can be detected in skin and kidney. Extensive searches in nucleic acid and protein databases revealed homologous sequences
in mouse, human and zebrafish. Mouse IRG1 mRNA is expressed in cultured macrophages as a response to bacterial lipopolysaccharide treatment.
Received: 27 April 2000 / Accepted: 13 June 2000 |
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| Keywords: | IRG1 Ectoderm Gastrulation Xenopus laevis |
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