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Pioglitazone/metformin adduct regulates insulin secretion and inhibits high glucose‐induced apoptosis via p21‐p53‐MDM2 signaling in INS‐1 cells |
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| Authors: | Rong‐Xing Liu Yan Ma Xue‐Lian Hu Yun‐Peng Liao Xiang‐Nan Hu Bai‐Cheng He Wen‐Juan Sun |
| Affiliation: | 1. Department of Pharmacology, School of Pharmacy, Chongqing Medical University, Chongqing, People's Republic of China;2. Key Laboratory for Biochemistry and Molecular Pharmacology of Chongqing, Chongqing Medical University, Chongqing, People's Republic of China;3. Department of Pharmacochemistry, School of Pharmacy, Chongqing Medical University, Chongqing, People's Republic of China;4. Department of Pharmacology, Xinqiao Hospital, Chongqing, People's Republic of China |
| Abstract: | |
| Keywords: | apoptosis INS‐1 cells insulin secretion p21‐p53‐MDM2 pioglitazone metformin adduct |