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Obacunone causes sustained expression of MKP‐1 thus inactivating p38 MAPK to suppress pro‐inflammatory mediators through intracellular MIF |
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| Authors: | Yuan Gao Rui Hou Fen Liu Haibo Liu Qiaoling Fei Yixin Han Runlan Cai Cheng Peng Yun Qi |
| Institution: | 1. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, P.R. China;2. Chegndu University of Traditional Chinese Medicine, Chengdu, P.R. China |
| Abstract: | |
| Keywords: | lipopolysaccharide (LPS) macrophages macrophage migration inhibitory factor (MIF) mitogen‐activated protein kinase phosphatase 1 (MKP‐1) obacunone (OBA) |