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Growth of doxorubicin‐resistant undifferentiated spindle‐cell sarcoma PDOX is arrested by metabolic targeting with recombinant methioninase |
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| Authors: | Kentaro Igarashi Shukuan Li Qinghong Han Yuying Tan Kei Kawaguchi Takashi Murakami Tasuku Kiyuna Kentaro Miyake Yunfeng Li Scott D. Nelson Sarah M. Dry Arun S. Singh Irmina A. Elliott Tara A. Russell Mark A. Eckardt Norio Yamamoto Katsuhiro Hayashi Hiroaki Kimura Shinji Miwa Hiroyuki Tsuchiya Fritz C. Eilber Robert M. Hoffman |
| Affiliation: | 1. AntiCancer, Inc., San Diego, California;2. Department of Surgery, University of California, San Diego, California;3. Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan;4. Department of Pathology, University of California, Los Angeles, California;5. Division of Hematology‐Oncology, University of California, Los Angeles, California;6. Division of Surgical Oncology, University of California, Los Angeles, California;7. Department of Surgery, Yale School of Medicine, New Haven, Connecticut |
| Abstract: | |
| Keywords: | doxorubicin patient‐derived orthotopic xenograft PDOX recombinant methioninase resistant undifferentiated spindle‐cell sarcoma |