AROuSing SIRT1: identification of a novel endogenous SIRT1 activator |
| |
| Authors: | Verdin Eric |
| |
| Affiliation: | Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA. everdin@gladstone.ucsf.edu |
| |
| Abstract: | SIRT1 is a protein deacetylase that regulates cellular responses to a variety of stresses. In a recent issue of Molecular Cell, Kim et al. (2007) report the identification of a cellular protein, AROS, that activates the SIRT1-mediated deacetylation of p53. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
