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Thiamine attenuates the hypertension and metabolic abnormalities in CD36-defective SHR: Uncoupling of glucose oxidation from cellular entry accompanied with enhanced protein O-GlcNAcylation in CD36 deficiency
Authors:Takao Tanaka  Koichi Sohmiya  Tatsuji Kono  Fumio Terasaki  Ryoichi Horie  Yasuhiko Ohkaru  Michiko Muramatsu  Shinji Takai  Mizuo Miyazaki  Yasushi Kitaura
Affiliation:(1) Third Division, Department of Internal Medicine, Osaka Medical College, Osaka, Japan;(2) Department of Pathology, Faculty of Medicine, Shimane University, Izumo, Japan;(3) Division of Laboratory Products, Dainippon Pharmaceutical Co., Ltd., Osaka, Japan;(4) Department of Pharmacology, Osaka Medical College, Osaka, Japan;(5) Third Division, Department of Internal Medicine, Osaka Medical College, Takatsuki, Osaka 569-8686, Japan
Abstract:
Keywords:CD36-deficiency  hexosamine biosynthetic pathway  metabolic syndrome  proteinO-GlcNAcylation  SHR  thiamine
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