Type I interferon as a stimulus for cross-priming |
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| Authors: | Le Bon Agnès Tough David F |
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| Affiliation: | INSERM U591 - Marie Curie Excellence Team, AVENIR Group, Faculté Necker, 156 rue de Vaugirard, 75015 Paris, France. lebon@necker.fr |
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| Abstract: | Type I interferon (IFN-alpha/beta) is induced rapidly by infection and is well recognised for its crucial role in innate defence. However, it is evident that IFN-alpha/beta also serves as a signal for the generation of adaptive immune responses. In this review, we focus on the involvement of IFN-alpha/beta in the induction of CD8+ T cell responses by cross-priming. |
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