Mechanisms of pathogenesis: evasion of killing by polymorphonuclear leukocytes |
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Authors: | Allen Lee-Ann H |
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Affiliation: | Department of Medicine and the Inflammation Program, MTF D154, University of Iowa and the VA Medical Center, 2501 Crosspark Road, Coralville, Iowa City, IA 55241, USA. lee-ann-allen@uiowa.edu |
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Abstract: | Few microorganisms evade killing by neutrophils. Summarized here are the mechanisms used by Yersinia, group A streptococci, Helicobacter, Ehrlichia and Francisella to block phagocytosis, disrupt phagosome maturation or perturb the respiratory burst. Also discussed are mechanisms used by neutrophils to control organisms that replicate inside macrophages. |
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