Antioxidant properties of fungal melanin pigments |
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| Authors: | V V Shcherba V G Babitskaya V P Kurchenko N V Ikonnikova T A Kukulyanskaya |
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| Institution: | (1) Present address: Belarussian Academy of Sciences, Institute of Microbiology, Zhodinskaya ul. 2, 220141 Minsk, Belarus |
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| Abstract: | Fungal melanin pigments were shown to display a high antioxidant activity. An increase in the number of methyl substituents
in benzidine molecules of melanins obtained from micromycetes and macromycetes was accompanied by a decrease in the efficiency
of inhibition of peroxidase-mediated oxidation. Melanins were found to have considerable gene-protecting properties. Pigments
isolated from macromycetes and applied at a much lower concentration than those obtained from micromycetes prevented damage
to bacteriophage-λ DNA induced by products of peroxidase-mediated degradation of aminobiphenyls. |
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