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Upgrading Laccase Production and Biochemical Properties: Strategies and Challenges
Authors:Brandt Bertrand  Fernando Martínez‐Morales  María R Trejo‐Hernández
Institution:Department of Environmental Biotechnology, Centro de Investigación en Biotecnología, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos, México
Abstract:Improving laccases continues to be crucial in novel biotechnological developments and industrial applications, where they are concerned. This review breaks down and explores the potential of the strategies (conventional and modern) that can be used for laccase enhancement (increased production and upgraded biochemical properties such as stability and catalytic efficiency). The challenges faced with these approaches are briefly discussed. We also shed light on how these strategies merge and give rise to new options and advances in this field of work. Additionally, this article seeks to serve as a guide for students and academic researchers interested in laccases. This document not only gives basic information on laccases, but also provides updated information on the state of the art of various technologies that are used in this line of investigation. It also gives the readers an idea of the areas extensively studied and the areas where there is still much left to be done. © 2017 American Institute of Chemical Engineers Biotechnol. Prog., 33:1015–1034, 2017
Keywords:chemical modification  genetic engineering  laccase  laccase improvement  laccase production  native enzymes  traditional strategies
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