Four New Diterpene Glucosides from Perovskia atriplicifolia |
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Authors: | Lu Gao Jun Zhou Le‐Yu Zhu Juan‐Rong Zhang Yu‐Xing Jing Jia‐Wen Zhao Xiang‐Zhong Huang Gan‐Peng Li Zhi‐Yong Jiang Da‐Yuan Xue |
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Affiliation: | 1. College of Life & Environmental Sciences, Minzu University of China, Beijing, P. R. China;2. Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming, P. R. China |
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Abstract: | Four new diterpene glucosides, namely perovskiaditerpenosides A – D ( 1 – 4 ), were isolated from the BuOH extract of Perovskia atriplicifolia. Their structures were well elucidated by chemical methods and comprehensive spectroscopic analyses including MS, IR, and NMR (1D and 2D). The newly isolated compounds were screened for their cytotoxic activity against HepG2, NB4, HeLa, K562, MCF7, PC3, and HL60. The obtained results indicated that the new compounds possessed considerable cytotoxic activity. |
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Keywords: | Labiatae
Perovskia atriplicifolia
Diterpene glucosides Perovskiaditerpenosides A  –   D Cytotoxic activities |
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