Comparison of Phytochemical Composition and Biological Activities of Rubus ulmifolius Extracts Originating from Four Regions of Tunisia |
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| Authors: | Sonia Tabarki Chedia Aouadhi Kaouther Mechergui Khaoula Mkadmini Hammi Riadh Ksouri Aly Raies Lamjed Toumi |
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| Institution: | 1. Laboratory of Sylvo – Pastoral Resources of Tabarka, Institute of Sylvo‐Pastoral, Jendouba University, Tabarka, Tunisia;2. Laboratory of Medicinal and Aromatic Plants, LPAM, Biotechnology Center of Borj Cedria, (CBBC), Hammam‐Lif, Tunisia;3. Laboratory of Epidemiology and Veterinary Microbiology, Group of Bacteriology and Biotechnology, Pasteur Institute of Tunisia (IPT), Tunis, Tunisia;4. National Institute for Research in Rural Engineering, Water and Forestry, Ariana, Tunisia;5. Laboratory of Microorganisms and Active Biomolecules, Faculty of Sciences of Tunis, University of Tunis EL Manar, Tunis, Tunisia |
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| Abstract: | In the current study, the phenolic composition, antioxidant and antimicrobial activities of extracts from Rubus ulmifolius Schott leaves harvested in four localities (Sejnen, Tabarka, Faija and Ain drahem) in Tunisia were investigated for the first time. Great differences were found for the chemical composition, total phenol contents and biological activities among the evaluated extracts. HPLC analysis of methanolic extracts showed that the dominant compounds were kaempferol 3‐O‐rutinoside and naringenine. In addition, significant correlations were observed between antioxidant activities and phenolic contents. In fact, leaves collected from Sejnen presented higher total phenol content (53.32 mg GAE/g DW) and antioxidant activities (IC50 = 39.40 mg/l) than the others samples. All extracts showed significant antimicrobial activity against six used bacteria with the inhibition zones diameters and minimal inhibitory concentration values were in the range of 8 – 16 mm and 6.25 – 25 mg/ml, respectively. The highest antimicrobial activities were recorded in Sejnen extract against Gram‐positive bacteria. |
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| Keywords: |
Rubus ulmifolius
Antibacterial activity Antioxidant activity Chemical composition Secondary metabolites |
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