光交联水凝胶在组织工程中的研究进展

由于生物相容性、可降解性、与天然细胞外基质结构的相似性,水凝胶成为组织工程的研究热点与重点。基于原位形成和可注射性、与现有加工技术(3D打印、静电纺丝)的兼容性,光交联水凝胶在组织工程领域广泛应用。综述了近年来光交联水凝胶在组织工程领域的研究进展,包括其在软骨组织、骨组织、脂肪组织、牙周组织和皮肤组织方面的研究思路及应用进展,以期为后续光交联水凝胶作为组织工程支架的研究提供参考。

Research Progress of Photocrosslinked Hydrogel in Tissue Engineering

Due to the biocompatibility, degradability, and similarity to the structure of natural extracellular matrix, hydrogel has become a research hotspot and focus of tissue engineering. Based on in-situ formation and injectability, and compatibility with existing processing technologies (3D printing, electrospinning), photocrosslinked hydrogels are widely used in the field of tissue engineering. In this paper, recent advances in the field of tissue engineering in photocrosslinked hydrogels are reviewed, including new advances in cartilage, bone, adipose and periodontal tissues. The paper reviews the photocrosslinked hydrogels and provides relevant references for future research.