Analogues of 2-crotonyloxymethyl-(4R,5R,6R)-4,5,6-trihydroxycyclohex-2-enone (COTC) with anti-tumor properties |
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| Authors: | Arthurs Claire L Wind Natasha S Whitehead Roger C Stratford Ian J |
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| Affiliation: | School of Chemistry, University of Manchester, Oxford Road, Manchester M13 9PL, UK. |
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| Abstract: | The syntheses of three novel analogues of the naturally occurring cytotoxic agent COTC are described and the results of bioassays of the target compounds against two lung cancer cell lines are presented. |
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