Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis |
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Authors: | Robert D Inman Basil Chiu |
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Institution: | (1) Division of Genes and Development, Toronto Western Research Institute, 399 Bathurst Street, M5T 2S8 Toronto, ON, Canada;(2) Department of Medicine, University of Toronto, 190 Elizabeth Street, M5G 2C4 Toronto, ON, Canada |
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Abstract: | Introduction We have previously observed that Brown Norway (BN) rats display a relative resistance to experimental Chlamydia-induced arthritis. In the present study, we examine an environmental toxin, mercuric chloride (HgCl2), as a modulator of this innate resistance to arthritis. |
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