The role of cellular active stresses in shaping the zebrafish body axis期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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The role of cellular active stresses in shaping the zebrafish body axis

Institution:	1. Mechanobiology Institute, National University of Singapore, Singapore;2. Department of Biological Sciences, National University of Singapore, Singapore;3. Institute of Molecular and Cell Biology, A1Star, Singapore;4. Warwick Medical School, University of Warwick, Coventry, United Kingdom

Abstract:	Tissue remodelling and organ shaping during morphogenesis are products of mechanical forces generated at the cellular level. These cell-scale forces can be coordinated across the tissue via information provided by biochemical and mechanical cues. Such coordination leads to the generation of complex tissue shape during morphogenesis. In this short review, we elaborate the role of cellular active stresses in vertebrate axis morphogenesis, primarily using examples from postgastrulation development of the zebrafish embryo.

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