Trace elements under the spotlight: A powerful nutritional tool in cancer |
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| Affiliation: | 1. Unitat de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d’Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, C. Sant Joan s/n, 43201, Reus, Spain;2. Department of Radiation Oncology, Hospital Universitari de Sant Joan, Institut d’Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Av. Doctor Josep Laporte 2, 43204, Reus, Spain;1. Department of Public Health, Faculty of Medicine, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic;2. Department of Respiratory Diseases, University Hospital Brno and Faculty of Medicine, Masaryk University, Jihlavská 20, 625 00, Brno, Czech Republic;3. Research Centre for Toxic Compounds in the Environment (RECETOX), Faculty of Science, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic;4. Institute of Analytical Chemistry of the Czech Academy of Sciences, Veveří 97, 602 00, Brno, Czech Republic;5. Institute of Laboratory Research on Geomaterials, Faculty of Natural Sciences, Comenius University in Bratislava, Slovakia;1. Physics Department, NOVA School of Science and Technology, NOVA University Lisbon, 2829-516, Caparica, Portugal;2. LIBPhys - Laboratory for Instrumentation, Biomedical Engineering and Radiation Physics, Portugal;3. Anatomy Department, NOVA Medical School, NOVA University Lisbon, 1169-056, Lisbon, Portugal;1. Department of Biological Sciences, University of Waikato, Hamilton, New Zealand;2. Waikato Clinical Campus, University of Auckland, Hamilton, New Zealand;3. Oncology Department, Waikato Hospital, Hamilton, New Zealand;1. Medical Biomaterial Research Center (MBRC), Tehran University of Medical Sciences, Tehran, Iran;2. Department of Toxicology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran;1. Department of Pediatrics, All India Institute of Medical Sciences, Jodhpur, 342005, India;2. WQMG/DEST Division, Defence Research and Development Organization, Jodhpur, 342011, India;3. Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, Jodhpur, 342005, India;4. Department of Biochemistry, All India Institute of Medical Sciences, Jodhpur, 342005, India;5. Department of Pediatrics, All India Institute of Medical Sciences, Jodhpur, 342005, India |
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| Abstract: | Cancer is the second leading cause of death worldwide. Research on the relationships between trace elements (TE) and the development of cancer or its prevention is a field that is gaining increasing relevance. This review provides an evaluation of the effects of TE (As, Al, B, Cd, Cr, Cu, F, I, Pb, Li, Mn, Hg, Mo, Ni, Se, Si, Sn, V and Zn) intake and supplementation in cancer risk and prevention, as well as their interactions with oncology treatments. Advancements in the knowledge of TE, their dietary interactions and their main food sources can provide patients with choices that will help them to improve their quality of life and therapy outcomes. This approach could open new opportunities for treatments based on the integration of conventional therapies (chemotherapy, radiotherapy, and immunotherapy) and dietary interventions that provide advanced personalized treatments. |
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| Keywords: | Cancer Cancer treatment Nutrition Trace elements |
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