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Prospects and future perspectives of selenium nanoparticles: An insight of growth promoter,antioxidant and anti-bacterial potentials in productivity of poultry
Institution:1. Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Zografos, Panepistimiopolis, Athens, 15784, Greece;2. Laboratory of Environmental Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Zografos, Panepistimiopolis, Athens, 15784, Greece;3. General Hospital “LAIKO”, Athens, 11527, Greece;1. Physics Department, NOVA School of Science and Technology, NOVA University Lisbon, 2829-516, Caparica, Portugal;2. LIBPhys - Laboratory for Instrumentation, Biomedical Engineering and Radiation Physics, Portugal;3. Anatomy Department, NOVA Medical School, NOVA University Lisbon, 1169-056, Lisbon, Portugal;1. Medical Biomaterial Research Center (MBRC), Tehran University of Medical Sciences, Tehran, Iran;2. Department of Toxicology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran;1. College of Biotechnology and Sericultural Research Institute, Jiangsu University of Science and Technology, Zhenjiang, 212018, PR China;2. College of Agriculture, Anshun University, Anshun, 561000, PR China
Abstract:Nanoparticles have been attracted attention in poultry research due to their low toxicity, higher bio-availability, high surface area with sustained drug release. Dietary supplementation with selenium nanoparticles (Se-NPs) plays a regulatory role in maintaining growth performance, feed conversion ratio (FCR), antioxidant defense as well as microbial control. Se-NPs have emerging importance in modulating intestinal health through the maintenance of beneficial microbes (microflora) as well as the production of short-chain fatty acids (SCFA). Se-NPs regulate intrinsic redox status by scavenging free radicals. The antioxidant potentiality of Se-NPs is influenced by the activation of the seleno-enzymes such as thioredoxin reductase and glutathione peroxidase family (GPx) involved in scavenging of Reactive Oxygen Species (ROS). The emerging significance of Se-NPs on antimicrobial activity has been exploited due to their bio-accumulative effects and biocompatibility potentiality in the cellular systems against poultry pathogens. The present review highlights on growth performance, antioxidant defense, and anti-bacterial potentiality of Se-NPs in poultry and also provide insight into its significance in the poultry industry.
Keywords:Se-NPs  Oxidative stress  Growth performance  Anti-bacterial effect  Feed conversion ratio (FCR)
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