DNA vaccines: designing strategies against parasitic infections |
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Authors: | Catherine Ivory Kris Chadee |
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Affiliation: | Institute of Parasitology of McGill University, Macdonald Campus, 21,111 Lakeshore Road, Ste, Anne de Bellevue, Quebec, Canada, H9X 3V9. kris.chadee@mcgill.ca. |
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Abstract: | The complexity of parasitic infections requires novel approaches to vaccine design. The versatility of DNA vaccination provides new perspectives. This review discusses the use of prime-boost immunizations, genetic adjuvants, multivalent vaccines and codon optimization for optimal DNA vaccine design against parasites. |
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