Structure of the serotype f polysaccharide antigen of Streptococcus mutans |
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Authors: | D G Pritchard S M Michalek J R McGhee R L Furner |
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Institution: | Department of Microbiology, University of Alabama at Birmingham 35294. |
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Abstract: | The structure of the serotype f polysaccharide antigen of Streptococcus mutans was determined by methylation analysis, periodate oxidation, and partial methanolysis, and the configuration of the anomeric linkages by 13C-n.m.r. spectroscopy, indicating the trisaccharide repeating unit----3)-alpha-L-Rhap-(1----2)-alpha-D-Glcp-(1----3)]-alpha-L-+ ++Rhap- (1----. The structure of the backbone of the polysaccharide was confirmed by demonstrating immunological identity between the product of Smith degradation of the S. mutans serotype f antigen and the group A-variant streptococcal polysaccharide. |
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