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Albizosides D and E, two new cytotoxic triterpene saponins from Albizia chinensis
Authors:Rui Liu  Xiao-Guang Chen  Jian-Jun Zhang
Affiliation:Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education and Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People’s Republic of China
Abstract:Two oleanane-type triterpene saponins, named albizosides D and E (1 and 2), together with a known compound, Julibroside J8 (3), were isolated from the stem bark of Albizia chinensis. The structures of compounds 1 and 2 were established by 1D, 2D NMR experiments, and chemical methods, and they showed moderate cytotoxic activity against a small panel of human tumor cell lines.
Keywords:Albizia chinensis   Triterpene saponin   Albizoside D   Albizoside E   Cytotoxic activity
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