Syntheses of novel azasugar-containing mimics of heparan sulfate fragments as potential heparanase inhibitors |
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| Authors: | Kirsty A Allen Gillian Norris Derek K Watt |
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| Institution: | a Carbohydrate Chemistry, Industrial Research Limited, Gracefield Rd, Lower Hutt, New Zealand
b Institute of Molecular Biosciences, Massey University, Private Bag 11222, Palmerston North, New Zealand |
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| Abstract: | A series of eight novel, highly modified mono-, di- and trisaccharide derivatives, each containing an iminoalditol moiety, has been synthesized in the quest for potential heparanase inhibitors. |
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| Keywords: | Iminoalditol Heparan sulfate Heparanase Inhibitor |
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