Seven new vernocuminosides from the stem bark of Vernonia cumingiana Benth |
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| Authors: | Jing Liu Haining Lv Yong Li Xianfu Wu Yuanyan Liu |
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| Affiliation: | Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education & Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Xiannongtan Street, Beijing 100050, People’s Republic of China |
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| Abstract: | Seven new stigmastane-type steroidal glycosides, vernocuminosides H-N, have been isolated from the stem bark of Vernonia cumingiana Benth. The structures of these compounds were determined by NMR spectrometric methods including HSQC, HMBC, 1H-1H COSY, and NOE, as well as circular dichroism experiments. Anti-inflammatory activities of vernocuminosides I and K-N were determined. |
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| Keywords: | Vernonia cumingiana Stigmastane Circular dichroism Anti-inflammatory activity |
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