Effect of Bicuculline on the GABA Receptor of the Crayfish Neuromuscular Junction |
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Authors: | A TAKEUCHI KAYOKO ONODERA |
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Institution: | 1.Department of Physiology, School of Medicine,Juntendo University,Hongo, Tokyo |
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Abstract: | SINCE it was reported that bicuculline is a specific antagonist of γ-aminobutyric acid (GABA)1–3, much attention has been paid to the action of this alkaloid on cortical neurones4–6. Thus it seemed worthwhile to test the mode of action of bicuculline on the inhibitory neuromuscular junction of the crayfish, where the action of GABA has been well documented7,8. |
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