Homologues of isomeric dideoxynucleosides as potential antiviral agents: synthesis of isodideoxynucleosides with a furanethanol sugar moiety. |
| |
| Authors: | X Zheng V Nair |
| |
| Affiliation: | Department of Chemistry, University of Iowa, Iowa City 52242, USA. |
| |
| Abstract: | The synthesis of a homologues series of compounds related to (R, S)-isodideoxynucleosides has been completed by coupling a variety of natural purine and pyrimidine bases with a modified sugar intermediate. This sugar precursor was prepared regiospecifically and stereospecifically from D-glucose. |
| |
| Keywords: | |
|
|
