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Protective groups in the chemical synthesis of oligoribonucleotides
Authors:A. V. Aralov  O. G. Chakhmakhcheva
Affiliation:1. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow, 117997, Russia
Abstract:The methods of chemical oligoribonucleotide synthesis and the protective groups used are reviewed. The latest data on the protection of 2′-OH functions of nucleotide derivatives used as monomers for the RNA synthesis are comprehensively discussed.
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