Protective groups in the chemical synthesis of oligoribonucleotides |
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Authors: | A. V. Aralov O. G. Chakhmakhcheva |
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Affiliation: | 1. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow, 117997, Russia
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Abstract: | The methods of chemical oligoribonucleotide synthesis and the protective groups used are reviewed. The latest data on the protection of 2′-OH functions of nucleotide derivatives used as monomers for the RNA synthesis are comprehensively discussed. |
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