The impact of media composition and petite mutation on the longevity of a polyploid brewing yeast strain |
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Authors: | Powell C D Quain D E Smart K A |
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Affiliation: | School of Biological and Molecular Sciences, Oxford Brookes University, Oxford, UK. |
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Abstract: | Ageing in Saccharomyces cerevisiae is a finite phenomenon, determined by replicative, rather than chronological lifespan. Yeast physiological condition is known to influence industrial fermentation performance, however, until recently cellular senescence has not been considered as a brewing yeast stress factor. A polyploid lager yeast (BB11) and a brewery isolate, exhibiting petite mutation were analysed for longevity. It was observed that mitochondrial deficiency induced a reduction in lifespan. In addition, replicative capacity was perceived to be dependent on environmental conditions. |
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