Steroid transformations with Exophiala jeanselmei var. lecanii-corni and Ceratocystis paradoxa |
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| Authors: | Porter R B Gallimore W A Reese P B |
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| Institution: | Chemistry Department, University of the West Indies, Mona, Kingston, Jamaica. |
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| Abstract: | The fungi Exophiala jeanselmei var. lecanii-corni IMI (International Mycological Institute) 312989, UAMH (University of Alberta Microfungus Collection and Herbarium) 8783] and Ceratocystis paradoxa (IMI 374529, UAMH 8784) have been examined for their potential in steroid biotransformation. The study has determined that E. jeanselmei var. lecanii-corni effected overall anti-Markovnikov hydration on dehydroisoandrosterone, and side-chain degradation on a variety of pregnanes. Both ascomycetes were found to carry out redox reactions of alcohols and ketones as well as 1,4 reduction of alpha,beta-unsaturated carbonyl systems. |
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