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Optimization of static magnetic field parameters improves analgesic effect in mice
Authors:László János  Reiczigel Jeno  Székely László  Gasparics Antal  Bogár István  Bors László  Rácz Bernadette  Gyires Klára
Affiliation:Section for Mathematics, Hungarian Academy of Sciences, Budapest, Hungary. laszloj@office.mta.hu
Abstract:The present study deals with the analgesic effect induced by static magnetic fields (SMF) in mice exposed to the field with their whole body. It discusses how the effect depends on the distribution of the magnetic field, that is, on the specification and arrangement of the applied individual permanent magnets. A critical analysis of different magnet arrangements is given. As a result the authors propose a magnet arrangement recipe that achieves an analgesic effect of over 80% in the writhing test. This is a widely accepted screening method for animal pain and predictor of human experimental results. As a non-drug, non-invasive, non-contact, non-pain, non-addictive method for analgesia with immediate and long-lasting effect based on the stimulus of the endogenous opioid network, the SMF treatment may attract the attention of medical doctors, nurses, magnet therapists, veterinarians, physiotherapists, masseurs, and fitness trainers among others.
Keywords:static magnetic field  analgesic effect  magnetic therapy  magnet  writhing test  antinociception  antinociceptive activity
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