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Polymorphic Inversions Underlie the Shared Genetic Susceptibility of Obesity-Related Diseases
Affiliation:1. Barcelona Institute for Global Health (ISGlobal), Barcelona 08003, Spain;2. IMIM (Hospital del Mar Research Institute), Barcelona 08003, Spain;3. Centro de Investigación Biomédica en Red en Epidemiologia y Salud Pública (CIBERESP), Barcelona 08003, Spain;4. Department of Mathematics, Universitat Autònoma de Barcelona (UAB), Barcelona 08193, Spain;5. Joint BSC-CRG-IRB Research Program in Computational Biology, Barcelona Supercomputing Center (BSC-CNS), Barcelona 08034, Spain;6. Department of Experimental and Health Sciences (CEXS), Universitat Pompeu Fabra, Barcelona 08003, Spain;7. Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Barcelona 08003, Spain;8. Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA;9. Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA;10. Department of Medicine, Harvard Medical School, Boston, MA 02115, USA;11. Estonian Genome Center, University of Tartu, Tartu 51010, Estonia;12. Institute of Molecular and Cell Biology, University of Tartu, 51010 Tartu, Estonia;13. Institució Catalana de Recerca i Estudis Avancats (ICREA), Barcelona 08003, Spain;14. Institute of Evolutionary Biology (CSIC-Universitat Pompeu Fabra), Barcelona 08003, Spain;15. Women’s and Children’s Hospital, South Australian Health and Medical Research Institute & University of Adelaide, Adelaide, SA 5005, Australia
Abstract:
Keywords:genetic inversions  obesity-related diseases  common diseases  obesity  diabetes  hypertension  asthma  human traits  disease co-occurrence  genomic variation
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