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Exogenous and endogenous increase in fungal GGPP increased fungal Taxol production
Authors:Soliman  Sameh S. M.  Mosa  Kareem A.  El-Keblawy  Ali A.  Husseiny  Mohamed I.
Affiliation:1.Sharjah Institute for Medical Research and College of Pharmacy, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates
;2.Faculty of Pharmacy, Zagazig University, Zagazig, Egypt
;3.Department of Applied Biology, University of Sharjah, Sharjah, United Arab Emirates
;4.Department of Translational Research & Cellular Therapeutics, Beckman Research Institute of City of Hope, Duarte, CA, 91010-3000, USA
;
Abstract:Applied Microbiology and Biotechnology - Taxol is an anticancer identified in both endophytic fungus and its host plant. Plant Taxol is a diterpenoid with geranylgeranyl diphosphate (GGPP) mediates...
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