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Identification and Characterization of a Novel Single Domain Antibody Against Ebola Virus
Authors:Wang  Rui  Zhang  Haiwei  Peng  Cheng  Shi  Jian  Zhang  Huajun  Gong  Rui
Affiliation:1.CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China2.University of Chinese Academy of Sciences, Beijing, 100049, China
Abstract:Virologica Sinica - Ebola virus (EBOV) belongs to the Filoviridae family and causes severe illnesses such as hemorrhagic fever with a high mortality rate up to 90%. Now two antibody drugs termed...
Keywords:Ebola virus (EBOV)   Constant domain 2 (CH2 domain)   C-based single domain antibody (C-sdAb)   Neutralize   Fusion loop  
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