Absence of genotoxic activity of refined smoke flavor (RSF) in two bacterial short-term tests |
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| Authors: | J Jenek P Quillardet D Chomiak A Borys M Hofnung |
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| Institution: | Unité de Programmation Moléculaire et Toxicologie Génétique, CNRS LA271, Institut Pasteur, Paris, France. |
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| Abstract: | The genotoxic activities of refined smoke flavor (RSF) produced in Poland and used in food processing were investigated in 2 bacterial short-term tests. Its mutagenic activity was examined in the Salmonella/histidine plate assay and its SOS-inducing capacity in the SOS Chromotest both without and with 'activation' by a rat liver homogenate. No genotoxic activity was detected using these 2 bacterial tests. |
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