| 血浆蛋白C、蛋白S抗凝体系的研究进展 |
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| 引用本文： | 易正戟. 血浆蛋白C、蛋白S抗凝体系的研究进展[J]. 上海生物医学工程, 2002, 23(1): 34-36 |
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| 作者姓名： | 易正戟 |
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| 作者单位： | 广东省农业科学院前沿动物保健技术中心 广东510640 |
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| 摘 要： | 蛋白C是一种维生素K依赖糖蛋白，它为血浆丝氨酸蛋白酶酶原；凝血酶能将蛋白C转化为活化蛋白C（APC），在一种叫蛋白S（PS）的APC协同因子存在时，APC发挥抗凝活性，蛋白C和蛋白S缺陷或缺乏可引起动、静脉血栓形成。
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| 关 键 词： | 蛋白C 蛋白S 抗凝系统 研究进展 生化结构 生物学功能 |
Research Progress of Protein C and Protein S Anticogulant System in Plasma |
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| Qianyan Animal Health Technology CenterGuangdong Academy of Agriculture Science,Yi ZhengJi. Research Progress of Protein C and Protein S Anticogulant System in Plasma[J]. Shanghai Journal of Biomedical Engineering, 2002, 23(1): 34-36 |
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| Authors: | Qianyan Animal Health Technology CenterGuangdong Academy of Agriculture Science Yi ZhengJi |
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| Affiliation: | Qianyan Animal Health Technology CenterGuangdong Academy of Agriculture Science,510640Yi ZhengJi |
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| Abstract: | Protein C is a Vitamin K-dependent glycoprotein and plasma serine protease precursor. Thrombin converts Protein C into activated protein C(APC). APC,in the presence of cofactor called Protein S(PS), exerts an anticoagulant action. According to the present study,we know that the deficiency of Protein C and Protein S can give rise to vevous or arterial thromboeambolism(40%-60%). |
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| Keywords: | Protein C Protein S anticoagulant system |
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