| Abstract: | The regulation of the synthesis of factor inhibiting the migration of macrophages in response to C. albicans antigen in CBA (H-2k) and C57BL/6 (H-2b) mice has been studied. The low level of macrophage migration inhibition factor in response to this antigen is due to the existence of cyclophosphamide-inhibited specific suppressors. Differences between various strains of mice ensue from different activity of suppressors of thymic origin, whose nature has been revealed as the result of the transfer of marrow cells treated with anti-Thy-1 serum. |
