Blazeispirols B, C, E and F, des-A-ergostane-type compounds, from the cultured mycelia of the fungus Agaricus blazei |
| |
| Authors: | Hirotani Masao Sai Kou Hirotani Seiko Yoshikawa Takafumi |
| |
| Institution: | School of Pharmaceutical Sciences, Kitasato University, Minato-ku, 108-8641, Tokyo, Japan. hirotanim@pharm.kitasato-u.ac.jp |
| |
| Abstract: | Four new des-A-ergostane derivatives including blazeispirols B, C, E and F were isolated from the cultured mycelia of fungus Agaricus blazei Murill and were established to be (20S, 22R, 23R, 24S)-14beta,22: 22,25-diepoxy-5-methoxy-des-A-ergosta-5,7,9,11-tetraen-23-ol; (20S, 22S, 23R, 24S)-14beta,22: 22,25-diepoxy-5-methoxy-des-A-ergosta-5,7,9-trien-23-ol; (20S, 22S, 23R, 24S)-14beta, 22: 22, 25-diepoxy-5-methoxy-des-A-ergosta-5,7,9,11-tetraene-19,23-diol and (20S, 22S, 23R, 24S)-14beta,22: 22,25-diepoxy-des-A-ergosta-5,7,9-triene-5,23-diol by comparison of extensive 1D and 2D NMR spectral data with that of blazeispirol A. |
| |
| Keywords: | Agaricus blazei Agaricaceae Basidiomycetes Higher fungi des-A-Steroid Blazeispirols A B C D E and F |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
