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Effect of low-intensity periodic-impulse laser UV radiation on the nucleic acid synthesis rate in proliferating and resting cells
Authors:T I Karu  G E Fedoseeva  E V Iudakhina  G S Kalendo  V V Lobko
Abstract:A study was made of the effect of the low intensity (10(-6)--10(3)/cm3) high repetition rate (pulse duration 18 nseconds, repetition rate 10 KHz) UV radiation (2nd harmonic of Cu vapour laser, lambda = 271.2 nm) on proliferating and resting cells (HeLa and fibroblast-like cells of Chinese hamster 431). The treatment within the dose range from 0.05 to 5 J/m3 stimulates DNA synthesis in the resting cells rather than in the proliferating ones. It was shown autoradiographically that, within the same dose range, the number of synthesizing cells increased in 2.5 hour.
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