Immunosuppressive constituents from Saussurea medusa. |
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| Authors: | Hongquan Duan Yoshihisa Takaishi Hiroshi Momota Yasukazu Ohmoto Takao Taki |
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| Institution: | Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, 770-8505, Tokushima, Japan. |
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| Abstract: | The methanol extract of Saussurea medusa Maxim afforded two lignans: 2alpha-guaicyl-4-oxo-6alpha-catechyl-3,7-dioxabicyclo 3.3.0]octane and 1alpha-hydroxy-2alpha,4alpha-guaicyl-3,7-dioxabicyclo3.3.0]octane; two chlorophyll derivatives: 13-epi-phaeophorbide-a and 13-epi-phaeophorbide-a methyl ester; one megastigmane derivative: 3beta-hydroxy-5alpha,6alpha-epoxy-7-megastigmen-9-one, along with 19 known compounds. Their structures were established on the basis of spectroscopic studies. |
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| Keywords: | Saussurea medusa Compositae Lignan Phaeophorbide Immunosuppressive activity |
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