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The Aspergillus fumigatus Secretome Alters the Proteome of Pseudomonas aeruginosa to Stimulate Bacterial Growth: Implications for Co-infection
Authors:Anatte Margalit  James C Carolan  David Sheehan  Kevin Kavanagh
Institution:Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland
Abstract:
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  • Highlights
    • ?Pseudomonas aeruginosa growth increases in Aspergillus fumigatus culture filtrates.
    • ?A. fumigatus culture filtrates are characterized by a range of peptidases and proteases.
    • ?LFQ proteomics characterizes the response of P. aeruginosa to A. fumigatus culture filtrates.
    • ?A. fumigatus creates an environment for P. aeruginosa to proliferate.
    Keywords:Bacteria  pathogens  secretome  cell biology  proliferation  Aspergillus  cystic fibrosis  Pseudomonas
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