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Peptide-based Interaction Proteomics
Institution:1. Institute of Molecular Life Sciences, University of Zurich, Zurich, Switzerland;2. Proteome Dynamics, Max Delbrück Center for Molecular Medicine, Berlin, Germany;3. Charité-Universitätsmedizin Berlin, Berlin, Germany
Abstract:
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  • Highlights
    • ?Peptide-based screens provide a scalable approach to study protein-protein interactions.
    • ?These screens help to characterize the function of structurally disordered regions.
    • ?The impact of posttranslational modifications can be directly investigated.
    Keywords:Peptide array  protein-protein interactions  affinity proteomics  peptide interactions  peptides  post-translational modifications  high throughput screening  mass spectrometry  intrinsically disordered regions  short linear motifs
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