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GLP-1 Receptor Signaling in Astrocytes Regulates Fatty Acid Oxidation,Mitochondrial Integrity,and Function
Affiliation:1. Max Planck Institute for Metabolism Research, Department of Neuronal Control of Metabolism, Gleueler Str. 50, 50931 Cologne, Germany;2. Center for Endocrinology, Diabetes and Preventive Medicine (CEDP), University Hospital Cologne, Kerpener Str. 26, 50924 Cologne, Germany;3. Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center of Molecular Medicine Cologne (CMMC), University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany;4. Institute for Zoology, Biocenter, University of Cologne, Zuelpicher Str. 47B, 50674 Cologne, Germany;5. Max Planck Institute for Biology of Aging, Joseph-Stelzmann-Str. 9b, 50931 Cologne, Germany;6. Program in Integrative Cell Signaling and Neurobiology of Metabolism, Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA;7. Institute for Mitochondrial Diseases and Aging, Medical Faculty, University of Cologne, 50931 Cologne, Germany;8. Department of Anatomy and Histology, University of Veterinary Medicine, 1078 Budapest, Hungary;9. National Center for Diabetes Research (DZD), Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany
Abstract:
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  • Keywords:GLP-1  astrocytes  mitochondria  ß-oxidation  stress response  FGF-21  glucose metabolism  obesity  energy homeostasis  hepatic glucose production
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