AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair
Affiliation:
3. Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030;4. Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030
Abstract:
Highlights
•Each component of the AMPK trimeric complex was profiled by interaction proteomics.
•The subunit composition of the AMPK complex directs interactions to distinct proteins.
•AMPK interacts with Artemis and plays a role in Non-Homologous End Joining.