Robust Summarization and Inference in Proteome-wide Label-free Quantification期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Robust Summarization and Inference in Proteome-wide Label-free Quantification

Institution:	1. Department of Applied Mathematics, Computer Science & Statistics, Ghent University, Belgium;2. VIB-UGent Center for Medical Biotechnology, VIB, Ghent, Belgium;3. Department of Biomolecular Medicine, Ghent University, Ghent, Belgium;4. Bioinformatics Institute Ghent, Ghent University, Ghent, Belgium

Abstract:	Download : Download high-res image (204KB) Download : Download full-size image Highlights •In depth performance assessment of leading tools for differential protein abundance. •Novel fast modular framework MSqRobSum for robust protein summarization and inference. •MsqRobSum outperforms leading protein summarization-based tools. •MSqRobSum is on par with top-performing peptide based tool MSqRob.

Keywords:	Biostatistics label-free quantification bioinformatics mass spectrometry bioinformatics software differential expression ridge regression shotgun proteomics summarization
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