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Hyperpolarized MRI of Human Prostate Cancer Reveals Increased Lactate with Tumor Grade Driven by Monocarboxylate Transporter 1
Institution:1. Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA;2. Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA;3. Radiochemistry and Molecular Imaging Probes (RIMP) Core, Memorial Sloan Kettering Cancer Center, New York, NY, USA;4. Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA;5. Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA;6. Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA;7. GE Healthcare, Toronto, ON, Canada;8. Berkshire Magnetics, Berkeley, CA, USA;9. GE Healthcare, Aurora, OH, USA;10. Weill Cornell Medical College, New York, NY, USA
Abstract:
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  • Keywords:metabolic imaging  glycolytic flux  hyperpolarized pyruvate
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