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Fast Quantitative Analysis of timsTOF PASEF Data with MSFragger and IonQuant

Authors:	Fengchao Yu Sarah E Haynes Guo Ci Teo Dmitry M Avtonomov Daniel A Polasky Alexey I Nesvizhskii

Institution:	1. Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA;2. Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA

Abstract:	Download : Download high-res image (118KB) Download : Download full-size image Highlights •MSFragger now supports raw timsTOF PASEF data. •IonQuant performs fast and accurate feature detection and quantification. •MSFragger and IonQuant provide excellent performance for timsTOF PASEF data. •Flexibility allows for complex analyses, such as semi-enzymatic and open search.

Keywords:	Bioinformatics label-free quantification protein identification algorithms tandem mass spectrometry ion mobility PASEF
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